RESPONSIBILITIES OF THE INVESTIGATORS

Source: UI-ACUREC handbook

A researcher planning to work with experimental animals should have undergone appropriate certified training on the care and use of experimental animals. Understanding the essence of appropriate care for the animals is critical to the outcome of the research. Read More

A researcher planning to work with experimental animals should have undergone appropriate certified training on the care and use of experimental animals. Understanding the essence of appropriate care for the animals is critical to the outcome of the research. 

The following are some of the key responsibilities of anyone involved in the handling and use of experimental animals; 

1. All protocols must first be submitted to the ANIMAL ETHICS COMMITTEE.

• This should be properly written according to the format provided and appropriate approval received before the commencement of the research. 

1. Consideration of alternatives (in vitro systems, computer simula­tions, and/or mathematical models) to reduce or replace the use of animals.
2. Design and performance of procedures on the basis of relevance to human or animal health, advancement of knowledge, or the good of society.
3. Use of appropriate species, quality, and number of animals.
4. Provision of appropriate animal transportation and husbandry directed and performed by qualified persons.
5. Provision of adequate veterinary care.
6. The conduct of experimentation on living animals exclusively by and/or under the close supervision of qualified and experienced scientists.
7. Avoidance or minimization of discomfort, distress, and pain in the animals.
8. Use of appropriate sedation, analgesia, and anaesthesia.
9. Establishment of humane endpoints.
10. Expect unannounced inspections of premises where animals used in research are maintained: animal quarters (macro-environment), laboratories, and procedure rooms (Surgical unit).